Frontier luminous strategy of functional silica nanohybrids in sensing and bioimaging: From ACQ to AIE

Fluorescent silica organic–inorganic nanohybrids which combine designable luminescence performance of organic fluorescent dyes and various outstanding advantages nanomaterials have attracted increasing research interests in these fascinating areas. Optical transparency facile functional modification properties material provide great opportunities to integrate desired molecules for frontier luminous applications. However, conventional are typically subject aggregation-caused quenching due their aggregation matrix, could be detrimental sensing biomedical The appearance aggregation-induced emission luminogens (AIEgens) paves a new way developing highly efficient (FSNs). FSNs with intensive obtained the formation aggregates restricted intramolecular motion AIEgens inorganic matrix. In this review, reported fabrication methodologies based on colloidal nanoparticles (SNs) mesoporous SNs including physical entrapment covalent strategies summarized. Especially, AIEgens-functionalized hybrid introduced detail. Furthermore, chemical sensing, biosensing, bioimaging applications resultant also discussed.